Description

MT-2 (Melanotan II) – Research Grade Peptide

Description:
MT-2 (Melanotan II) is a synthetic cyclic heptapeptide developed as an analogue of the natural α-melanocyte-stimulating hormone (α-MSH). By incorporating a stable lactam bridge and terminal modifications, MT-2 demonstrates enhanced melanocortin receptor affinity and metabolic stability, making it a valuable compound for biological and pharmacological research.

Research Significance:

• MC1R activation: Studied extensively as a model for pigmentation biology, melanogenesis, and UV-response signaling.
• MC3R & MC4R activation: Investigated in the context of appetite regulation, satiety, and energy balance.
• MC5R activation: Explored for roles in exocrine function and broader metabolic pathways.

Potential Applications in Research:

• Studying melanocortin receptor signaling in central and peripheral systems.
• Exploring pathways linked to pigmentation, metabolic regulation, and energy expenditure.
• Modeling hypothalamic control of appetite and satiety in preclinical settings.
• Examining the stability and pharmacological behavior of cyclic peptide analogues.

Background:
Melanotan II has been widely used in scientific investigations as a research tool for the melanocortin system. Its ability to interact with multiple melanocortin receptor subtypes provides insight into diverse physiological pathways, including pigmentation, metabolism, and energy regulation.

Specifications:

• Compound: MT-2 (Melanotan II, Research Grade)
• Form: Lyophilized powder
• Storage: Store at -20°C in a dry, dark place
• Stability: Stable for extended periods when properly stored

Important Notice:
This product is supplied strictly for laboratory research use only. It is not intended for human or veterinary use. No therapeutic or diagnostic claims are made.